Modulation of SF1 neuron activity coordinately regulates both feeding behavior and associated emotional states
Feeding requires the integration of homeostatic drives with emotional states relevant to food procurement in potentially hostile environments. The ventromedial hypothalamus (VMH) regulates feeding and anxiety, but how these are controlled in a concerted manner remains unclear. Using pharmacogenetic, optogenetic, and calcium imaging approaches with a battery of behavioral assays, we demonstrate that VMH steroidogenic factor 1 (SF1) neurons constitute a nutritionally sensitive switch, modulatin...Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
(Version of record, pdf, 3.8MB)
- Publisher copy:
- Copyright holder:
- Viskaitis et al
- Copyright date:
Copyright © 2017 The Authors.
This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
- CC Attribution (CC BY)
If you are the owner of this record, you can report an update to it here: Report update to this record