- Abstract:
-
Deep brain stimulation (DBS) is known to be an effective treatment for a variety of neurological disorders, including Parkinson's disease and essential tremor (ET). At present, it involves administering a train of pulses with constant frequency via electrodes implanted into the brain. New 'closed-loop' approaches involve delivering stimulation according to the ongoing symptoms or brain activity and have the potential to provide improvements in terms of efficiency, efficacy and reduction of si...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
- Files:
-
-
(pdf, 4.6MB)
-
- Publisher copy:
- 10.1371/journal.pcbi.1006575
-
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Computational Biology Journal website
- Volume:
- 15
- Issue:
- 8
- Pages:
- e1006575
- Publication date:
- 2019-08-08
- Acceptance date:
- 2019-06-07
- DOI:
- EISSN:
-
1553-7358
- ISSN:
-
1553-734X
- Pubs id:
-
pubs:1040492
- URN:
-
uri:b5d4fb30-85e6-4b19-aaba-68d05156caa8
- UUID:
-
uuid:b5d4fb30-85e6-4b19-aaba-68d05156caa8
- Local pid:
- pubs:1040492
- Language:
- English
- Copyright holder:
- Weerasinghe et al.
- Copyright date:
- 2019
- Notes:
- © 2019 Weerasinghe et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
Predicting the effects of deep brain stimulation using a reduced coupled oscillator model
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