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Thesis

Structural studies of the type three secretion system export apparatus

Abstract:

One of the most widespread bacterial secretion systems is the type three secretion system (T3SS), which is critical for the virulence of many pathogens and responsible for assembly of the bacterial flagellum. The virulence-associated T3SS is a molecular syringe that uses a highly conserved export apparatus (EA) to secrete effector proteins through a needle directly into the host cell cytoplasm. The flagellar T3SS secretes flagellar subunits through the EA which then self-assemble into a fi...

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Supervisor
Department:
Physical/Theoretical Chemistry
Role:
Supervisor
More from this funder
Name:
Wellcome Trust
Funding agency for:
Kuhlen, L
Grant:
109136/Z/15/A
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:b5cbc0c7-a077-4e47-a723-049b3ad47ea7
Deposit date:
2019-11-09

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