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Repairing damaged tendon and muscle: are mesenchymal stem cells and scaffolds the answer?

Abstract:

Mesenchymal stem cells (MSCs) have become an area of intense interest in the treatment of musculoskeletal conditions, such as muscle and tendon injury, as various animal and human trials have demonstrated that implantation with MSCs leads to improved healing and function. However, these trials have usually been relatively small scale and lacking in adequate controls. Additionally, the optimum source of these cells has yet to be determined, partly due to a lack of understanding as to how MSCs ...

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Publication status:
Published

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Publisher copy:
10.2217/rme.13.55

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
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Journal:
Regenerative medicine
Volume:
8
Issue:
5
Pages:
613-630
Publication date:
2013-09-01
DOI:
EISSN:
1746-076X
ISSN:
1746-0751
Source identifiers:
420694
Language:
English
Keywords:
Pubs id:
pubs:420694
UUID:
uuid:b570735e-90d4-4489-87a5-f03e0149a1be
Local pid:
pubs:420694
Deposit date:
2013-11-16

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