Repairing damaged tendon and muscle: are mesenchymal stem cells and scaffolds the answer?

Journal article

Mesenchymal stem cells (MSCs) have become an area of intense interest in the treatment of musculoskeletal conditions, such as muscle and tendon injury, as various animal and human trials have demonstrated that implantation with MSCs leads to improved healing and function. However, these trials have usually been relatively small scale and lacking in adequate controls. Additionally, the optimum source of these cells has yet to be determined, partly due to a lack of understanding as to how MSCs ...

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Authors: Davies, B; Morrey, M; Mouthuy, P; Baboldashti, N; Hakimi, O

• Publication status: Published
• Journal: Regenerative medicine
• Volume: 8
• Issue: 5
• Pages: 613-630
• Publication date: 2013-09-01
• DOI: 10.2217/rme.13.55
• EISSN: 1746-076X
• ISSN: 1746-0751
• Language: English
• Keywords: Mesenchymal Stromal Cells; Humans; Tissue Scaffolds; Muscles; Tendons; Animals; Clinical Trials as Topic; Mesenchymal Stem Cell Transplantation; Regeneration