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Journal article : Review

The methylation game: epigenetic and epitranscriptomic dynamics of 5-methylcytosine

Abstract:

DNA and RNA methylation dynamics have been linked to a variety of cellular processes such as development, differentiation, and the maintenance of genome integrity. The correct deposition and removal of methylated cytosine and its oxidized analogues is pivotal for cellular homeostasis, rapid responses to exogenous stimuli, and regulated gene expression. Uncoordinated expression of DNA/RNA methyltransferases and demethylase enzymes has been linked to genome instability and consequently to ca...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fcell.2022.915685

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Institution:
University of Oxford
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Oxford college:
Wadham College
Role:
Author
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Name:
Cancer Research UK
Grant:
24866
Publisher:
Frontiers Media
Journal:
Frontiers in Cell and Developmental Biology More from this journal
Volume:
10
Pages:
915685
Publication date:
2022-06-03
Acceptance date:
2022-05-06
DOI:
EISSN:
2296-634X
Pmid:
35721489
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1265957
Local pid:
pubs:1265957
Deposit date:
2022-11-09

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