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Where chloroquine still works: the genetic make-up and susceptibility of Plasmodium vivax to chloroquine plus primaquine in Bhutan

Abstract:

Bhutan has made substantial progress in reducing malaria incidence. The national guidelines recommend chloroquine (CQ) and primaquine (PQ) for radical cure of uncomplicated Plasmodium vivax, but the local efficacy has not been assessed. The impact of cases imported from India on the genetic make-up of the local vivax populations is currently unknown.Patients over 4 years of age with uncomplicated P. vivax mono-infection were enrolled into a clinical efficacy study and molecular survey. Study ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Files:
Publisher copy:
10.1186/s12936-016-1320-8

Authors


Wangchuk, S More by this author
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Funding agency for:
Price, RN
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Grant:
Project Grant awarded to TB (No. 109-01) and SW (No 103-01)
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Grant:
(Senior Fellowship in Clinical Science awarded to RNP, 091625)
Publisher:
BioMed Central Publisher's website
Journal:
Malaria Journal Journal website
Volume:
15
Issue:
1
Pages:
Article: 277
Publication date:
2016-05-12
DOI:
ISSN:
1475-2875
Pubs id:
pubs:623587
URN:
uri:b5484717-0eae-4c77-9383-9e02a6f11583
UUID:
uuid:b5484717-0eae-4c77-9383-9e02a6f11583
Local pid:
pubs:623587

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