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Journal article

Evidence for linkage of stature to chromosome 3p26 in a large U.K. Family data set ascertained for type 2 diabetes.

Abstract:

We have analyzed data from 573 pedigrees from the United Kingdom for evidence for linkage to loci influencing adult stature. Our data set comprised 1,214 diabetic and 163 nondiabetic siblings for whom height data were available. We used variance-components analysis implemented in GENEHUNTER 2 and a modification of the Haseman-Elston regression method, HE-COM. We found evidence for a locus on 3p26 (LOD score 3.17) influencing height in this adult sample, with less-significant evidence for loci...

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Publication status:
Published

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Publisher copy:
10.1086/338760

Authors


Wiltshire, S More by this author
Frayling, TM More by this author
Hattersley, AT More by this author
Hitman, GA More by this author
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Journal:
American journal of human genetics
Volume:
70
Issue:
2
Pages:
543-546
Publication date:
2002-02-05
DOI:
EISSN:
1537-6605
ISSN:
0002-9297
URN:
uuid:b538523d-efc4-49d2-8ca8-b1f13808c306
Source identifiers:
17921
Local pid:
pubs:17921

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