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Quantitative map of proteome dynamics during neuronal differentiation

Abstract:

Neuronal differentiation is a multistep process that shapes and re-shapes neurons by progressing through several typical stages, including axon outgrowth, dendritogenesis, and synapse formation. To systematically profile proteome dynamics throughout neuronal differentiation, we took cultured rat hippocampal neurons at different developmental stages and monitored changes in protein abundance using a combination of stable isotope labeling and high-resolution liquid chromatography-tandem mass sp...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher:
Elsevier Publisher's website
Journal:
Cell Reports Journal website
Volume:
18
Issue:
6
Pages:
1527-1542
Publication date:
2017-02-07
Acceptance date:
2017-01-11
DOI:
EISSN:
2211-1247
Pmid:
28178528
Source identifiers:
681337
Language:
English
Keywords:
Pubs id:
pubs:681337
UUID:
uuid:b515a6da-5573-4dc3-a117-85b917164361
Local pid:
pubs:681337
Deposit date:
2018-04-12

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