Journal article icon

Journal article

Antibody-mediated detection and physical properties of oligonucleotides labelled with multiple internal and terminal 2,4-dinitrophenyl groups.

Abstract:
DNP-labelled phosphoramidites have been used to synthesis oligonucleotides with multiple DNP reporter groups. The antibody-mediated detection and the stability of duplexes formed by these labelled oligonucleotides have been studied. A DNP-labelled deoxyuridine triphosphate has also been used to enzymatically incorporate DNP-labels into DNA via the polymerase chain reaction. The use of DNP-labelled primers in the PCR has also been investigated.

Actions


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Role:
Author
Journal:
Biomedical peptides, proteins and nucleic acids : structure, synthesis and biological activity
Volume:
2
Issue:
1
Pages:
7-12
Publication date:
1996-01-01
ISSN:
1353-8616
URN:
uuid:b50c2de3-b761-4758-ba0c-c700e7daad4a
Source identifiers:
400080
Local pid:
pubs:400080

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP