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Distribution of Bexsero® antigen sequence types (BASTs) in invasive meningococcal disease isolates: implications for immunisation

Abstract:

Serogroup B is the only major disease-associated capsular group of Neisseria meningitidis for which no protein-polysaccharide conjugate vaccine is available. This has led to the development of multi-component protein-based vaccines that target serogroup B invasive meningococcal disease (IMD), including Bexsero®, which was implemented for UK infants in 2015, and Trumenba®. Given the diversity of meningococcal protein antigens, post-implementation surveillance of IMD isolates, including charac...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.vaccine.2016.08.015

Authors


Brehony, C More by this author
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Department:
Oxford, Department for Continuing Education
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Funding agency for:
Rodrigues, CMC
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Funding agency for:
Maiden, MCJ
Meningitis Research Foundation More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Vaccine Journal website
Volume:
34
Issue:
39
Pages:
4690-4697
Publication date:
2016-08-09
Acceptance date:
2016-08-03
DOI:
ISSN:
1873-2518
Pubs id:
pubs:638041
URN:
uri:b4ff2e67-e65f-4974-8a1a-a78a9d5e6c26
UUID:
b4ff2e67-e65f-4974-8a1a-a78a9d5e6c26
Local pid:
pubs:638041

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