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Journal article

Plasma chemokine levels correlate with the outcome of antiviral therapy in patients with hepatitis C.

Abstract:

Chronic infection with the hepatitis C virus (HCV) is associated with failures of T-cell-mediated immune clearance and with abnormal B-cell growth and activation. We examined the levels of chemokines that bind to CXC chemokine receptor 3 (CXCR3) to determine whether such chemokines might play a role in the failure of the immune system to clear HCV infection. Elevations in CXC ligand 9 (CXCL9), CXCL10, and CXCL11 were observed in all patients with HCV. CXCR3 expression was increased significan...

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Publisher copy:
10.1182/blood-2005-01-0126

Authors


Marukian, S More by this author
Iwamaye, AE More by this author
Hembrador, E More by this author
Chambers, TJ More by this author
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Journal:
Blood
Volume:
106
Issue:
4
Pages:
1175-1182
Publication date:
2005-08-29
DOI:
EISSN:
1528-0020
ISSN:
0006-4971
URN:
uuid:b4c0430d-39d3-4b5b-99b8-894aa59503c9
Source identifiers:
426418
Local pid:
pubs:426418

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