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Comparison of artemether-lumefantrine and chloroquine with and without primaquine for the treatment of Plasmodium vivax infection in Ethiopia: A randomized controlled trial

Abstract:
Background Recent efforts in malaria control have resulted in great gains in reducing the burden of Plasmodium falciparum, but P. vivax has been more refractory. Its ability to form dormant liver stages confounds control and elimination efforts. To compare the efficacy and safety of primaquine regimens for radical cure, we undertook a randomized controlled trial in Ethiopia. Methods and findings Patients with normal glucose-6-phosphate dehydrogenase status... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pmed.1002299

Authors


Thriemer, K More by this author
Tadesse, Y More by this author
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More from this funder
Funding agency for:
Price, R
President's Malaria Initiative More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Medicine Journal website
Volume:
14
Issue:
5
Pages:
Article: e1002299
Publication date:
2017-05-16
DOI:
EISSN:
1549-1676
ISSN:
1549-1277
Pubs id:
pubs:695743
URN:
uri:b498e80b-ecf5-484a-b330-7672b5dbc724
UUID:
uuid:b498e80b-ecf5-484a-b330-7672b5dbc724
Local pid:
pubs:695743

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