Urinary peptide profiling identifies a panel of putative biomarkers for diagnosing and staging endometriosis.

Journal article

OBJECTIVE: To identify a potential diagnostic endometriosis marker using matrix-enhanced laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS)-based urinary proteomics. DESIGN: Prospective randomized pilot study. SETTING: University hospital, tertiary referral center for endometriosis. PATIENT(S): 53 women undergoing laparoscopic surgery for pain and/or infertility comprising 30 women without endometriosis and 23 with endometriosis. INTERVENTION(S): Laparoscopy and urine...

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Authors: El-Kasti, M; Wright, C; Fye, H; Roseman, F; Kessler, B

• Publication status: Published
• Journal: Fertility and sterility
• Volume: 95
• Issue: 4
• Pages: 1261-6.e1-6
• Publication date: 2011-03-01
• DOI: 10.1016/j.fertnstert.2010.11.066
• EISSN: 1556-5653
• ISSN: 0015-0282
• Language: English
• Keywords: Peptides; Protein Array Analysis; Adult; Biological Markers; Pilot Projects; Disease Progression; Young Adult; Humans; Female; Middle Aged; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Endometriosis; Prospective Studies