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Determination of the human brainstem respiratory control network and its cortical connections in vivo using functional and structural imaging.

Abstract:

This study combined functional and structural magnetic resonance imaging techniques, optimized for the human brainstem, to investigate activity in brainstem respiratory control centres in a group of 12 healthy human volunteers. We stimulated respiration with carbon dioxide (CO(2)), and utilized novel methodology to separate its vascular from its neuronal effects upon the blood oxygen level dependent (BOLD) signal. In the brainstem we observed activity in the dorsal rostral pons (representing ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neurosciences
Mitsis, GD More by this author
Harvey, AK More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Doctoral Training Centre - MPLS
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Journal:
NeuroImage
Volume:
44
Issue:
2
Pages:
295-305
Publication date:
2009-01-05
DOI:
EISSN:
1095-9572
ISSN:
1053-8119
URN:
uuid:b438ebbd-1ac3-4ee0-80ff-d07590a844fe
Source identifiers:
241163
Local pid:
pubs:241163

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