Large-scale spatial and temporal genetic diversity of feline calicivirus.

Journal article

Feline calicivirus (FCV) is an important pathogen of domestic cats and a frequently used model of human caliciviruses. Here we use an epidemiologically rigorous sampling framework to describe for the first time the phylodynamics of a calicivirus at regional and national scales. A large number of FCV strains cocirculated in the United Kingdom at the national and community levels, with no strain comprising more than 5% and 14% of these populations, respectively. The majority of strains exhibite...

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Authors: Coyne, K; Christley, R; Pybus, O; Dawson, S; Gaskell, R

• Publication status: Published
• Journal: Journal of virology
• Volume: 86
• Issue: 20
• Pages: 11356-11367
• Publication date: 2012-10-01
• DOI: 10.1128/jvi.00701-12
• EISSN: 1098-5514
• ISSN: 0022-538X
• Language: English
• Keywords: Cell Line; Vaccination; RNA, Viral; Sequence Alignment; Base Sequence; Antibodies, Viral; Viral Vaccines; Molecular Epidemiology; Cat Diseases; Great Britain; Phylogeny; Sequence Analysis, RNA; Longitudinal Studies; Caliciviridae Infections; Cross-Sectional Studies; Molecular Sequence Data; Animals; Genetic Variation; Cats; Calicivirus, Feline