Journal article icon

Journal article

Immune response to recombinant Burkholderia pseudomallei FliC

Abstract:

Burkholderia pseudomallei is a flagellated Gram-negative bacterium which is the causative agent of melioidosis. The disease poses a major public health problem in tropical regions and diabetes is a major risk factor. The high mortality rate of melioidosis is associated with severe sepsis which involves the overwhelming production of pro-inflammatory cytokines. Bacterial flagellar protein (flagellin) activates Toll-like receptor 5 (TLR5)-mediated innate immune signaling pathways and induces ad...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pone.0198906

Authors


Expand authors...

Contributors

Role:
Editor
Department:
Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand.
Royal Thai Goverment Scholarship More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS One Journal website
Volume:
13
Issue:
6
Pages:
e0198906
Publication date:
2018-06-14
Acceptance date:
2018-05-29
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Pubs id:
pubs:857660
URN:
uri:b3d4e2b4-9274-414d-9a90-c75573488b1b
UUID:
uuid:b3d4e2b4-9274-414d-9a90-c75573488b1b
Local pid:
pubs:857660
Language:
English
Keywords:

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP