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Zolmitriptan-induced growth hormone release in humans: mediation by 5-HT1D receptors?

Abstract:

RATIONALE: Effective neuroendocrine probes of 5-HT1B and 5-HT1D receptor function may facilitate investigation of the role of these receptor subtypes in the pathophysiology of depression and the mode of action of antidepressant medication. OBJECTIVE: To investigate the neuroendocrine profile of the 5-HT1B/1D receptor agonist, zolmitriptan, in healthy volunteers. METHODS: Twelve subjects entered a double-blind, placebo-controlled, cross-over design study of zolmitriptan (5 mg orally). Blood s...

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Publication status:
Published

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Publisher copy:
10.1007/s002130051052

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Journal:
Psychopharmacology
Volume:
145
Issue:
2
Pages:
223-226
Publication date:
1999-07-01
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
Source identifiers:
185766
Language:
English
Keywords:
Pubs id:
pubs:185766
UUID:
uuid:b3c88e53-6941-47ba-a0c3-12890798c5a0
Local pid:
pubs:185766
Deposit date:
2012-12-19

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