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Journal article

Putative cis-regulatory drivers in colorectal cancer.

Abstract:

The cis-regulatory effects responsible for cancer development have not been as extensively studied as the perturbations of the protein coding genome in tumorigenesis. To better characterize colorectal cancer (CRC) development we conducted an RNA-sequencing experiment of 103 matched tumour and normal colon mucosa samples from Danish CRC patients, 90 of which were germline-genotyped. By investigating allele-specific expression (ASE) we show that the germline genotypes remain important determina...

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Publication status:
Published

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Publisher copy:
10.1038/nature13602

Authors


Andersen, CL More by this author
Bramsen, JB More by this author
Rasmussen, MH More by this author
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Journal:
Nature
Volume:
512
Issue:
7512
Pages:
87-90
Publication date:
2014-08-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:b3c30461-4557-458f-ba64-cfd694865a82
Source identifiers:
479271
Local pid:
pubs:479271

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