Journal article
Affinity, kinetics, and thermodynamics of E-selectin binding to E-selectin ligand-1.
- Abstract:
-
E-selectin is an endothelial adhesion molecule, which mediates the tethering and rolling of leukocytes on vascular endothelium. It recognizes the glycoprotein E-selectin ligand-1 (ESL-1) as a major binding partner on mouse myeloid cells. Using surface plasmon resonance, we measured the kinetics and affinity of binding of monomeric E-selectin to ESL-1 isolated from mouse bone marrow cells. E-selectin bound to ESL-1 with a fast dissociation rate constant of 4.6 s(-1) and a calculated associatio...
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- Publication status:
- Published
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- Publisher copy:
- 10.1074/jbc.m104844200
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Authors
Bibliographic Details
- Journal:
- Journal of biological chemistry
- Volume:
- 276
- Issue:
- 34
- Pages:
- 31602-31612
- Publication date:
- 2001-08-01
- DOI:
- EISSN:
-
1083-351X
- ISSN:
-
0021-9258
- Source identifiers:
-
22292
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:22292
- UUID:
-
uuid:b3c2064b-097a-4cbd-bfa2-c9370a22f9f1
- Local pid:
- pubs:22292
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2001
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