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Anterior optic pathway pathology in CNS demyelinating diseases

Abstract:

The anterior optic pathway is one of the preferential sites of involvement in CNS inflammatory demyelinating diseases, such as multiple sclerosis and neuromyelitis optica, with optic neuritis being a common presenting symptom. What is more, optic nerve involvement in these diseases is often subclinical, with optical coherence tomography demonstrating progressive neuroretinal thinning in absence of optic neuritis. The pathological substrate for these findings is poorly understood and requires ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/brain/awac030

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Role:
Author
ORCID:
0000-0001-9409-6864
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Name:
Multiple Sclerosis Society UK
Grant:
98
Publisher:
Oxford University Press
Journal:
Brain More from this journal
Volume:
145
Issue:
12
Pages:
4308-4319
Publication date:
2022-02-03
Acceptance date:
2021-12-19
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
Pmid:
35134111
Language:
English
Keywords:
Pubs id:
1095598
Local pid:
pubs:1095598
Deposit date:
2022-02-14

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