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Journal article

Chick PTPsigma regulates the targeting of retinal axons within the optic tectum.

Abstract:

Chick PTPsigma (cPTPsigma), also known as CRYPalpha, is a receptor-like protein tyrosine phosphatase found on axons and growth cones. Putative ligands for cPTPsigma are distributed within basement membranes and on glial end feet of the retina, optic nerve, and optic tectum, suggesting that cPTPsigma signaling is occurring along the whole retinotectal pathway. We have shown previously that cPTPsigma plays a role in supporting the retinal phase of axon outgrowth. Here we have now addressed the ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Structural Biology
Role:
Author
Journal:
The Journal of neuroscience : the official journal of the Society for Neuroscience
Volume:
22
Issue:
12
Pages:
5024-5033
Publication date:
2002-06-05
EISSN:
1529-2401
ISSN:
0270-6474
URN:
uuid:b3a5e3e8-cd95-4090-94f2-34459f47ac91
Source identifiers:
26069
Local pid:
pubs:26069

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