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Journal article

Chick PTPsigma regulates the targeting of retinal axons within the optic tectum.

Abstract:

Chick PTPsigma (cPTPsigma), also known as CRYPalpha, is a receptor-like protein tyrosine phosphatase found on axons and growth cones. Putative ligands for cPTPsigma are distributed within basement membranes and on glial end feet of the retina, optic nerve, and optic tectum, suggesting that cPTPsigma signaling is occurring along the whole retinotectal pathway. We have shown previously that cPTPsigma plays a role in supporting the retinal phase of axon outgrowth. Here we have now addressed the ...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Biology
Role:
Author
Journal:
Journal of neuroscience : the official journal of the Society for Neuroscience
Volume:
22
Issue:
12
Pages:
5024-5033
Publication date:
2002-06-01
EISSN:
1529-2401
ISSN:
0270-6474
Source identifiers:
26069
Language:
English
Keywords:
Pubs id:
pubs:26069
UUID:
uuid:b3a5e3e8-cd95-4090-94f2-34459f47ac91
Local pid:
pubs:26069
Deposit date:
2012-12-19

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