Journal article icon

Journal article

Horizontal DNA transfer mechanisms of bacteria as weapons of intragenomic conflict

Abstract:

Horizontal DNA transfer (HDT) is a pervasive mechanism of diversification in many microbial species, but its primary evolutionary role remains controversial. Much recent research has emphasised the adaptive benefit of acquiring novel DNA, but here we argue instead that intragenomic conflict provides a coherent framework for understanding the evolutionary origins of HDT. To test this hypothesis, we developed a mathematical model of a clonally descended bacterial population undergoing HDT throu...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pbio.1002394

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Expand authors...
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Biology Journal website
Volume:
14
Issue:
3
Pages:
e1002394
Publication date:
2016-03-02
Acceptance date:
2016-01-29
DOI:
EISSN:
1545-7885
ISSN:
1544-9173
Pmid:
26934590
Source identifiers:
609514
Language:
English
Keywords:
Pubs id:
pubs:609514
UUID:
uuid:b399ae13-09da-43a9-b72d-8fb5f816a9bf
Local pid:
pubs:609514
Deposit date:
2017-01-03

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP