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Journal article

Localized rest and stress human cardiac creatine kinase reaction kinetics at 3 T

Abstract:

Changes in the kinetics of the creatine kinase (CK) shuttle are sensitive markers of cardiac energetics but are typically measured at rest and in the prone position. This study aims to measure CK kinetics during pharmacological stress at 3 T, with measurement in the supine position. A shorter “stressed saturation transfer” (StreST) extension to the triple repetition time saturation transfer (TRiST) method is proposed. We assess scanning in a supine position and validate the MR measurement aga...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/nbm.4085

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
ORCID:
0000-0001-7159-7025
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Publisher:
Wiley Publisher's website
Journal:
NMR in Biomedicine Journal website
Volume:
Online publication
Article number:
e4085
Publication date:
2019-03-28
Acceptance date:
2019-01-28
DOI:
EISSN:
1099-1492
ISSN:
0952-3480
Source identifiers:
985579
Keywords:
Pubs id:
pubs:985579
UUID:
uuid:b38fb7c4-3832-43b2-964d-44cb3cdaca03
Local pid:
pubs:985579
Deposit date:
2019-03-28

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