Mapping developmental trajectories of attention and working memory in fragile X syndrome: developmental freeze or developmental change?

Journal article

Fragile X syndrome (FXS) has a characteristic cognitive "signature" that by late childhood includes core weaknesses in attention and working memory (WM), but their earlier developmental trajectories remain uncharted. Using a combined cross-sectional and prospective longitudinal design, we tested whether early profiles of attention and WM impairment in FXS indicate developmental freeze or developmental change. In Study 1, 26 young boys with FXS and 55 typically developing (TD) boys completed t...

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Authors: Cornish, K; Cole, V; Longhi, E; Karmiloff-Smith, A; Scerif, G

• Publication status: Published
• Journal: Development and psychopathology
• Volume: 25
• Issue: 2
• Pages: 365-376
• Publication date: 2013-05-01
• DOI: 10.1017/s0954579412001113
• EISSN: 1469-2198
• ISSN: 0954-5794
• Language: English
• Keywords: Male; Memory, Short-Term; Humans; Longitudinal Studies; Intelligence; Child; Cross-Sectional Studies; Neuropsychological Tests; Child, Preschool; Child Development; Prospective Studies; Developmental Disabilities; Fragile X Syndrome; Attention