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Journal article

Reproducible and replicable pain research: a critical review

Abstract:

Recently, the degree to which scientific publications provides a reliable source of information has come under intense scrutiny. Reports suggest that a substantial amount of published literature is likely to be biased, distorted, and non-reproducible. This cuts across basic, pre-clinical, and clinical research. It has been estimated that non-reproducible preclinical research consumes $28 billion/year (USD) and that 85% of biomedical research resources are wasted on biased research.

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1097/j.pain.0000000000001254

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Oxford college:
Wadham College
ORCID:
0000-0003-4349-7195
Cashin, AG More by this author
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National Health and Medical Research Council More from this funder
National Institute for Health Research More from this funder
Laura and John Arnold Foundation More from this funder
Kadoorie Charitable Foundation More from this funder
Ireland Interdisciplinary Capacity Enhancement More from this funder
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Publisher:
Lippincott, Williams and Wilkins Publisher's website
Journal:
Pain Journal website
Volume:
159
Issue:
9
Pages:
1683–1689
Publication date:
2018-04-23
Acceptance date:
2018-04-17
DOI:
EISSN:
1872-6623
ISSN:
0304-3959
Pubs id:
pubs:846241
URN:
uri:b37b1f8f-f185-4e7a-b53c-8bad6c699f89
UUID:
uuid:b37b1f8f-f185-4e7a-b53c-8bad6c699f89
Local pid:
pubs:846241

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