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Travelling-wave ion mobility and negative ion fragmentation of high-mannose N-glycans.

Abstract:

The isomeric structure of high-mannose N-glycans can significantly impact biological recognition events. Here, the utility of travelling-wave ion mobility-mass spectrometry (TW IM-MS)for isomer separation of high-mannose N-glycans is investigated. Negative ion fragmentation using collisioninduced dissociation (CID) gave more informative spectra than positive ion spectra with mas sdifferent fragment ions characterizing many of the isomers. Isomer separation by ion mobility in both ionization m...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/jms.3738

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International AIDS Vaccine Initiative Neutralizing Antibody Center More from this funder
Publisher:
Wiley Publisher's website
Journal:
Journal of Mass Spectrometry Journal website
Volume:
51
Issue:
3
Pages:
219-235
Publication date:
2016-03-05
DOI:
EISSN:
1096-9888
ISSN:
1076-5174
URN:
uuid:b35c16e7-7df9-4a68-899f-2e5049533ca7
Source identifiers:
609364
Local pid:
pubs:609364

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