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Journal article

Structure and chromosomal location of the mouse interleukin-12 p35 and p40 subunit genes.

Abstract:

Interleukin-12 (IL-12) is a heterodimeric cytokine composed of p35 and p40 subunits and is required for induction of T helper 1 (Th1) responses. Knowledge of how the IL-12 gene is regulated will permit an understanding of susceptibility and resistance to pathogenic microbes and to autoiummune diseases. In this report, we provide the gene structures, nucleotide sequences and chromosomal assignment for the p35 and p40 subunits of mouse IL-12. The p35 and p40 subunit genes are distributed over 8...

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Publication status:
Published

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Publisher copy:
10.1002/eji.1830260606

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
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Journal:
European journal of immunology
Volume:
26
Issue:
6
Pages:
1222-1227
Publication date:
1996-06-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:b3595da1-0f0d-42b3-a467-d63f18937f82
Source identifiers:
16742
Local pid:
pubs:16742

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