- Abstract:
-
Interleukin-12 (IL-12) is a heterodimeric cytokine composed of p35 and p40 subunits and is required for induction of T helper 1 (Th1) responses. Knowledge of how the IL-12 gene is regulated will permit an understanding of susceptibility and resistance to pathogenic microbes and to autoiummune diseases. In this report, we provide the gene structures, nucleotide sequences and chromosomal assignment for the p35 and p40 subunits of mouse IL-12. The p35 and p40 subunit genes are distributed over 8...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/eji.1830260606
-
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- Journal:
- European journal of immunology
- Volume:
- 26
- Issue:
- 6
- Pages:
- 1222-1227
- Publication date:
- 1996-06-05
- DOI:
- EISSN:
-
1521-4141
- ISSN:
-
0014-2980
- URN:
-
uuid:b3595da1-0f0d-42b3-a467-d63f18937f82
- Source identifiers:
-
16742
- Local pid:
- pubs:16742
- Copyright date:
- 1996
Journal article
Structure and chromosomal location of the mouse interleukin-12 p35 and p40 subunit genes.
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