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Blood stage antimalarial efficacy of primaquine in Plasmodium vivax malaria.

Abstract:

The blood stage antimalarial efficacy of primaquine (0.25 mg of base/kg of body weight/day over 14 days) and chloroquine (25 mg of base/kg over 3 days) were compared in 85 adult Thai men with acute Plasmodium vivax malaria. Most (75%) had at least one malaria episode previously. Parasite clearance times after primaquine alone (n = 30) were slower than after chloroquine (n = 30) or combined chloroquine-primaquine (n = 25), but all patients had a satisfactory initial therapeutic response. P. vi...

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Publication status:
Published

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Publisher copy:
10.1093/infdis/169.4.932

Authors


Pukrittayakamee, S More by this author
Vanijanonta, S More by this author
Chantra, A More by this author
Clemens, R More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Journal:
The Journal of infectious diseases
Volume:
169
Issue:
4
Pages:
932-935
Publication date:
1994-04-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:b31da9c5-3da2-408c-863a-8c00955be68d
Source identifiers:
44516
Local pid:
pubs:44516

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