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The pathogenesis of severe malaria in African children.

Abstract:

The pathogenesis of severe, Plasmodium falciparum malaria in African children is considered in the context of its two major clinical syndromes: malaria with respiratory distress; and malaria with neurological disturbance. Respiratory distress is an important prognostic marker in children with P. falciparum infections. In the majority of cases it reflects an underlying metabolic acidosis, usually associated with lactic acidaemia. Hypovolaemia and anaemia are important underlying factors. The s...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
Volume:
90
Issue:
4
Pages:
395-402
Publication date:
1996-08-05
EISSN:
1364-8594
ISSN:
0003-4983
URN:
uuid:b309da13-2475-455c-bf37-6ad1f0e8ac25
Source identifiers:
45340
Local pid:
pubs:45340

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