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Journal article

Models for studying coronary artery stenting

Abstract:
Angioplasty and stenting are the most commonly performed revascularization procedures for symptomatic coronary artery disease. Stenting achieves immediate and stable arterial patency but induces a complex biological response in the vessel wall, which can lead to intimal hyperplasia and restenosis. The biophysical properties of stents have been investigated with computational and in vitro models, and the arterial response to stenting addressed using a range of in vivo models. This article reviews the strengths and limitations of these experimental systems, and their applicability to human coronary intervention. © 2006 Elsevier Ltd. All rights reserved.

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Publisher copy:
10.1016/j.ddmod.2006.10.001

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author


Journal:
Drug Discovery Today: Disease Models More from this journal
Volume:
3
Issue:
3
Pages:
297-303
Publication date:
2006-01-01
DOI:
ISSN:
1740-6757


Language:
English
Pubs id:
pubs:106014
UUID:
uuid:b2fd0b9f-f622-4fdd-b94b-f34197936026
Local pid:
pubs:106014
Source identifiers:
106014
Deposit date:
2012-12-19

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