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Do animal models have a place in the genetic analysis of quantitative human behavioural traits?

Abstract:

It seems that the genetic basis of common psychiatric diseases such as schizophrenia and manic-depressive psychosis is amenable to the genetic mapping strategies that have been successful in other complex disorders such as diabetes. The next challenge is the genetic dissection of quantitative behavioural traits such as mood, personality and intelligence. Quantitative traits pose new problems for gene cloning experiments. We argue that one way forward is by using animal models. One of the feat...

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Publication status:
Published

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Publisher copy:
10.1007/s001090050054

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Journal:
Journal of molecular medicine (Berlin, Germany)
Volume:
74
Issue:
9
Pages:
515-521
Publication date:
1996-09-05
DOI:
EISSN:
1432-1440
ISSN:
0946-2716
URN:
uuid:b2e113fa-87e4-4d4f-926f-fcf1a60ae3b3
Source identifiers:
35987
Local pid:
pubs:35987

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