Journal article icon

Journal article

Self tolerance is H-2-restricted.

Abstract:

H-2 restriction is an established characteristic of T-cell behaviour and, in effect, it means that mouse T cells are activated against foreign antigens only if those antigens are presented in a membrane association with molecules of the mouse major histocompatibility complex, H-2. Whether T-cell inactivation or tolerance is also H-2-restricted is a question which has been tested directly and indirectly several times in the past. In each case the answer was 'No' but in each case the answer was...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/308738a0

Authors


Matzinger, P More by this author
Zamoyska, R More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Nature
Volume:
308
Issue:
5961
Pages:
738-741
Publication date:
1984
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:b29ef504-c833-4f94-9fba-d37770e6d30e
Source identifiers:
4463
Local pid:
pubs:4463

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP