Journal article icon

Journal article

Cortical cholinergic input is required for normal auditory perception and experience-dependent plasticity in adult ferrets.

Abstract:

The nucleus basalis (NB) in the basal forebrain provides most of the cholinergic input to the neocortex and has been implicated in a variety of cognitive functions related to the processing of sensory stimuli. However, the role that cortical acetylcholine release plays in perception remains unclear. Here we show that selective loss of cholinergic NB neurons that project to the cortex reduces the accuracy with which ferrets localize brief sounds and prevents them from adaptively reweighting au...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Cordery, PM More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Journal:
The Journal of neuroscience : the official journal of the Society for Neuroscience
Volume:
33
Issue:
15
Pages:
6659-6671
Publication date:
2013-04-05
DOI:
EISSN:
1529-2401
ISSN:
0270-6474
URN:
uuid:b2781271-bdbc-4ba0-aa12-258254cc1cbb
Source identifiers:
383225
Local pid:
pubs:383225

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP