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A novel cohort of cancer-testis biomarker genes revealed through meta-analysis of clinical data sets.

Abstract:

The identification of cancer-specific biomolecules is of fundamental importance to the development of diagnostic and/or prognostic markers, which may also serve as therapeutic targets. Some antigenic proteins are only normally present in male gametogenic tissues in the testis and not in normal somatic cells. When these proteins are aberrantly produced in cancer they are referred to as cancer/testis (CT) antigens (CTAs). Some CTA genes have been proven to encode immunogenic proteins that have ...

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Authors


Sammut, SJ More by this author
Feichtinger, J More by this author
Wakeman, JA More by this author
Larcombe, L More by this author
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Journal:
Oncoscience
Volume:
1
Issue:
5
Pages:
349-359
Publication date:
2014
EISSN:
2331-4737
URN:
uuid:b26b22d2-2dc1-42da-90e3-575b5bc17582
Source identifiers:
491074
Local pid:
pubs:491074

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