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Differences in immunization site pain in toddlers vaccinated with either the 10- or the 13-valent pneumococcal conjugate vaccine

Abstract:
We investigated immediate immunization pain in 12-month-old children randomized to receive a booster dose of either the 10- (PCV-10) or the 13-valent (PCV-13) pneumococcal conjugate vaccine. Pain was assessed using validated pain assessment tools and crying time. PCV-13 recipients had significantly higher scores on the observer-rated modified behavioral pain scale than did those receiving PCV-10, but the differences were small.Clinical trial registration at Clinicaltrials.gov (NCT01443416).
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1097/inf.0000000000001894

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care; Primary Care Health Sciences
Oxford college:
All Souls College
ORCID:
0000-0001-6324-6559
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Grant:
Oxford Biomedical Research Centre
GSK Biologicals More from this funder
Publisher:
Lippincott, Williams & Wilkins Publisher's website
Journal:
Pediatric Infectious Disease Journal Journal website
Volume:
37
Issue:
4
Pages:
e103–e106
Publication date:
2018-01-10
Acceptance date:
2018-01-06
DOI:
EISSN:
1532-0987
ISSN:
0891-3668
Pubs id:
pubs:819889
URN:
uri:b265f061-fa25-4fc8-87be-15d92eb77ba3
UUID:
uuid:b265f061-fa25-4fc8-87be-15d92eb77ba3
Local pid:
pubs:819889

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