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Identification of prostate-specific antigen (PSA) isoforms in complex biological samples utilizing complementary platforms.

Abstract:

Measurements of the prostate-specific antigen (PSA) levels in blood are widely used as diagnostic, predictive and prognostic marker of prostate disease. The selective detection of molecular forms of PSA can contribute clinically to meaningful enhancements of the conventional PSA-test. As it is plausible that an in-depth search for structural variants of PSA gene products may increase our ability to discriminate distinct patho-biological basis and stages of prostate diseases, we have developed...

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Publisher copy:
10.1016/j.jprot.2010.01.008

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
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Journal:
Journal of proteomics
Volume:
73
Issue:
6
Pages:
1137-1147
Publication date:
2010-04-05
DOI:
EISSN:
1876-7737
ISSN:
1874-3919
URN:
uuid:b249e66e-b2a4-4bd1-bf85-59b7e733c4b6
Source identifiers:
365904
Local pid:
pubs:365904

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