Journal article
A quantitative analysis of cardiac myocyte relaxation: a simulation study
- Abstract:
-
The determinants of relaxation in cardiac muscle are poorly understood, yet compromised relaxation accompanies various pathologies and impaired pump function. In this study, we develop a model of active contraction to elucidate the relative importance of the [Ca2+]i transient magnitude, the unbinding of Ca2+ from troponin C (TnC), and the length-dependence of tension and Ca2+ sensitivity on relaxation. Using the framework proposed by one of our researchers, we extensively reviewed experimenta...
Expand abstract
Actions
Authors
Bibliographic Details
- Journal:
- Biophys J
- Volume:
- 90
- Issue:
- 5
- Pages:
- 1697-722
- Publication date:
- 2006-01-01
Item Description
- UUID:
-
uuid:b224a26c-259a-4ed7-9774-4ed9cb07097a
- Local pid:
- cs:1527
- Deposit date:
- 2015-03-31
Terms of use
- Copyright date:
- 2006
If you are the owner of this record, you can report an update to it here: Report update to this record