Journal article
Hypoxia response elements.
- Abstract:
-
Hypoxia-inducible factor-1 (HIF-1) has been shown to mediate the transcriptional activation of its target genes in response to oxygen concentration, most likely via a pathway involving a specific oxygen sensor. Molecular cloning of HIF-1 has shown that this widely expressed, DNA binding transcription factor is a heterodimer of two proteins, HIF-1 alpha and HIF-1 beta. A major control of HIF-1 activity by oxygen tension is achieved by changes in the level of the HIF-1 alpha subunit, which comp...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Oncology research
- Volume:
- 9
- Issue:
- 6-7
- Pages:
- 327-332
- Publication date:
- 1997-01-01
- EISSN:
-
1555-3906
- ISSN:
-
0965-0407
- Source identifiers:
-
23461
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:23461
- UUID:
-
uuid:b2186518-3284-4d6b-a4d4-69e62cab7259
- Local pid:
- pubs:23461
- Deposit date:
- 2012-12-19
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- Copyright date:
- 1997
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