- Abstract:
-
The genes that are mutated in inherited cancer syndromes are often involved in the pathogenesis of sporadic cancers of the types that characterize those syndromes. In colorectal cancer such loci include the familial adenomatous polyposis (APC) gene and the hereditary nonpolyposis colorectal cancer (DNA mismatch repair) genes. Juvenile hamartomatous polyposis syndromes, which include Juvenile Polyposis and Cowden disease, also predispose to colorectal cancer. The gene for Cowden disease has re...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/s0165-4608(97)00011-3
-
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- Journal:
- Cancer genetics and cytogenetics
- Volume:
- 97
- Issue:
- 1
- Pages:
- 64-69
- Publication date:
- 1997-08-05
- DOI:
- EISSN:
-
1873-4456
- ISSN:
-
0165-4608
- URN:
-
uuid:b2185bb4-ce31-4fe3-b458-bc0b0e490f6d
- Source identifiers:
-
72324
- Local pid:
- pubs:72324
- Language:
- English
- Keywords:
- Copyright date:
- 1997
Journal article
Allele loss in colorectal cancer at the Cowden disease/juvenile polyposis locus on 10q.
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