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Avidity of serogroup A meningococcal IgG antibodies after immunization with different doses of a tetravalent A/C/Y/W135 polysaccharide vaccine.

Abstract:

In the absence of an affordable conjugate meningococcal vaccine, mass vaccination campaigns with polysaccharide vaccines are the means to control meningitis epidemics in sub-Saharan Africa. Facing global vaccine shortage, the use of reduced doses, which have been shown to be protective by serum bactericidal activity, can save many lives. In this study, we investigated the antibody responses and avidity of IgG antibodies evoked against the serogroup A capsule of Neisseria meningitidis by diffe...

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Publication status:
Published

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Authors


Bårnes, GK More by this author
Rosenqvist, E More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Tropical Medicine
Caugant, DA More by this author
Journal:
Scandinavian journal of immunology
Volume:
74
Issue:
1
Pages:
87-94
Publication date:
2011-07-05
DOI:
EISSN:
1365-3083
ISSN:
0300-9475
URN:
uuid:b214fac3-9d9d-45db-a162-908995c2a473
Source identifiers:
120126
Local pid:
pubs:120126

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