Cannabis, cannabinoids and the endocannabinoid system – is there therapeutic potential for inflammatory bowel disease?
Cannabis sativa and its extracts have been used for centuries both medicinally and recreationally. There is accumulating evidence that exogenous cannabis and related cannabinoids improve symptoms associated with inflammatory bowel disease such as pain, loss of appetite, and diarrhoea. In vivo, exocannabinoids have been demonstrated to improve colitis, mainly in chemical models. Exocannabinoids signal through the endocannabinoid system, an increasingly understood network of endogenous lipid l...Expand abstract
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- European Crohn’s and Colitis Organisation
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Copyright © 2018 European Crohn’s and Colitis Organisation.
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