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A strategy for the integration of QTL, gene expression, and sequence analyses.

Abstract:

Although hundreds if not thousands of quantitative trait loci (QTL) have been described for a wide variety of complex traits, only a very small number of these QTLs have been reduced to quantitative trait genes (QTGs) and quantitative trait nucleotides (QTNs). A strategy, Multiple Cross Mapping (MCM), is described for detecting QTGs and QTNs that is based on leveraging the information contained within the haplotype structure of the mouse genome. As described in the current report, the strateg...

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Publication status:
Published

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Publisher copy:
10.1007/s00335-003-2277-9

Authors


Hitzemann, R More by this author
Malmanger, B More by this author
Hitzemann, B More by this author
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Journal:
Mammalian genome : official journal of the International Mammalian Genome Society
Volume:
14
Issue:
11
Pages:
733-747
Publication date:
2003-11-05
DOI:
EISSN:
1432-1777
ISSN:
0938-8990
URN:
uuid:b201e14c-4691-4866-bc4d-d3caece6b5d6
Source identifiers:
38808
Local pid:
pubs:38808

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