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Going around in circles: virulence plasmids in enteric pathogens

Abstract:

Plasmids have a major role in the development of disease caused by enteric bacterial pathogens. Virulence plasmids are usually large (>40 kb) low copy elements and encode genes that promote host–pathogen interactions. Although virulence plasmids provide advantages to bacteria in specific conditions, they often impose fitness costs on their host. In this Review, we discuss virulence plasmids in Enterobacteriaceae that are important causes of diarrhoea in humans, Shigella spp., Salmonella sp...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1038/s41579-018-0031-2

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
Oxford college:
Exeter College
More from this funder
Funding agency for:
Pilla, G
Publisher:
Springer Nature Publisher's website
Journal:
Nature Reviews Microbiology Journal website
Volume:
16
Issue:
8
Pages:
484–495
Publication date:
2018-05-31
Acceptance date:
2018-04-25
DOI:
EISSN:
1740-1534
ISSN:
1740-1526
Pubs id:
pubs:857097
URN:
uri:b1f3c48f-bfb9-42de-876c-00b609b8565a
UUID:
uuid:b1f3c48f-bfb9-42de-876c-00b609b8565a
Local pid:
pubs:857097

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