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Association of the 5- HTTLPR genotype and unipolar depression: a meta-analysis.

Abstract:

BACKGROUND: We sought to ascertain the strength of evidence for association between the 5-HTTLPR polymorphism and unipolar depression. METHOD: We applied meta-analytic techniques to data from relevant published studies, and obtained an estimate of the likely magnitude of effect of any association. We also tested for possible publication bias, and explored the impact of various study design characteristics on the magnitude of the observed effect size. RESULTS: Meta-analysis indicated evidence...

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Publication status:
Published

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Publisher copy:
10.1017/s0033291710000516

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
Journal:
Psychological medicine
Volume:
40
Issue:
11
Pages:
1767-1778
Publication date:
2010-11-05
DOI:
EISSN:
1469-8978
ISSN:
0033-2917
URN:
uuid:b1d1e93a-a085-4b44-84ab-9f443aae99ba
Source identifiers:
97308
Local pid:
pubs:97308

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