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Understanding pneumococcal serotype 1 biology through population genomic analysis

Abstract:

Background

Pneumococcus kills over one million children annually and over 90 % of these deaths occur in low-income countries especially in Sub-Saharan Africa (SSA) where HIV exacerbates the disease burden. In SSA, serotype 1 pneumococci particularly the endemic ST217 clone, causes majority of the pneumococcal disease burden. To understand the evolution of the virulent ST217 clone, we analysed ST217 whole genomes from isolates sampled from African and Asian countries.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12879-016-1987-z

Authors


Publisher:
BioMed Central
Journal:
BMC Infectious Diseases More from this journal
Volume:
16
Issue:
1
Pages:
649
Publication date:
2016-11-01
Acceptance date:
2016-10-30
DOI:
ISSN:
1471-2334
Language:
English
Keywords:
Pubs id:
pubs:659521
UUID:
uuid:b1bcec19-c00b-45f8-8c61-891e25c22ee4
Local pid:
pubs:659521
Source identifiers:
659521
Deposit date:
2016-11-15

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