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Understanding pneumococcal serotype 1 biology through population genomic analysis

Abstract:

Background

Pneumococcus kills over one million children annually and over 90 % of these deaths occur in low-income countries especially in Sub-Saharan Africa (SSA) where HIV exacerbates the disease burden. In SSA, serotype 1 pneumococci particularly the endemic ST217 clone, causes majority of the pneumococcal disease burden. To understand the evolution of the virulent ST217 clone, we analysed ST217 whole genomes from isolates sampled from African and Asian countries.

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s12879-016-1987-z

Authors


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Commonwealth Scholarship Commission More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
BMC Infectious Diseases Journal website
Volume:
16
Issue:
1
Pages:
649
Publication date:
2016-11-05
Acceptance date:
2016-10-30
DOI:
ISSN:
1471-2334
Pubs id:
pubs:659521
URN:
uri:b1bcec19-c00b-45f8-8c61-891e25c22ee4
UUID:
uuid:b1bcec19-c00b-45f8-8c61-891e25c22ee4
Local pid:
pubs:659521

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