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Enhanced non-vitreous cryopreservation of immortalized and primary cells by ice-growth inhibiting polymers.

Abstract:

Cell cryopreservation is an essential tool in modern biotechnology and medicine. The ability to freeze, store and distribute materials underpins basic cell biology and enables storage of donor cells needed for transplantation and regenerative medicine. However, many cell types do not survive freezing and the current state-of-the-art involves the addition of significant amounts of organic solvents as cryoprotectants, which themselves can be cytotoxic, or simply interfere with assays. A key cau...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1039/c6bm00129g

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Department:
Oxford, MSD, Obstetrics & Gynaecology
Role:
Author
Advantage West Midlands More from this funder
European Regional Development Fund More from this funder
Royal Society More from this funder
Warwick Transatlantic Fellowship More from this funder
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Publisher:
Royal Society of Chemistry Publisher's website
Journal:
Biomaterials Science Journal website
Volume:
4
Issue:
7
Pages:
1079-1084
Publication date:
2016-05-05
Acceptance date:
2016-05-01
DOI:
ISSN:
2047-4849 and 2047-4830
Pubs id:
pubs:619942
URN:
uri:b19ed957-e33e-4c37-a48e-3ad44c4b6a37
UUID:
uuid:b19ed957-e33e-4c37-a48e-3ad44c4b6a37
Local pid:
pubs:619942
Language:
English
Keywords:

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