Journal article icon

Journal article

Par3/Bazooka and phosphoinositides regulate actin protrusion formation during Drosophila dorsal closure and wound healing.

Abstract:

Effective wound closure mechanisms are essential for maintenance of epithelial structure and function. The repair of wounded epithelia is primarily driven by the cells bordering the wound, which become motile after wounding, forming dynamic actin protrusions along the wound edge. The molecular mechanisms that trigger wound edge cells to become motile following tissue damage are not well understood. Using wound healing and dorsal closure in Drosophila, we identify a direct molecular link betwe...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1242/dev.089557

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
Journal:
Development (Cambridge, England)
Volume:
140
Issue:
4
Pages:
800-809
Publication date:
2013-02-05
DOI:
EISSN:
1477-9129
ISSN:
0950-1991
URN:
uuid:b19495d8-cd88-4b14-ad16-af6d18d4f081
Source identifiers:
374265
Local pid:
pubs:374265

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP