Journal article icon

Journal article

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells.

Abstract:

Foxp3 activity is essential for the normal function of the immune system. Two types of regulatory T (T reg) cells express Foxp3, thymus-generated natural T reg (nT reg) cells, and peripherally generated adaptive T reg (iT reg) cells. These cell types have complementary functions. Until now, it has not been possible to distinguish iT reg from nT reg cells in vivo based solely on surface markers. We report here that Neuropilin 1 (Nrp1) is expressed at high levels by most nT reg cells; in contra...

Expand abstract

Actions


Access Document


Publisher copy:
10.1084/jem.20120914

Authors


Expand authors...
Journal:
The Journal of experimental medicine
Volume:
209
Issue:
10
Pages:
1723-S1
Publication date:
2012-09-05
DOI:
EISSN:
1540-9538
ISSN:
0022-1007
URN:
uuid:b171af9e-e937-4228-8d63-75d6a5990f2e
Source identifiers:
426243
Local pid:
pubs:426243

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP