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Journal article

Functional analysis of dendritic cell-T cell interaction in sarcoidosis.

Abstract:

The primary cause of the intense immune response in sarcoidosis is unclear. Potentially, a functional abnormality in dendritic cells (DCs) could cause a reduction in clearance of antigen and downstream persistence in immune activity. In this study, we investigate the interaction between monocyte-derived dendritic cells and T cells in patients with sarcoidosis compared to normal controls (n = 8 each) by examining the kinetics of autologous and allogeneic mixed leucocyte reactions over 9-10 day...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
Journal:
Clinical and experimental immunology
Volume:
159
Issue:
1
Pages:
82-86
Publication date:
2010-01-05
DOI:
EISSN:
1365-2249
ISSN:
0009-9104
URN:
uuid:b14884bb-bafc-4e3b-8e69-86f6b5a21363
Source identifiers:
34953
Local pid:
pubs:34953

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