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EvoRegen in Animals: Time to uncover deep conservation or convergence of adult stem cell evolution and regenerative processes

Abstract:

How do animals regenerate specialised tissues or their entire body after a traumatic injury, how has this ability evolved and what are the genetic and cellular components underpinning this remarkable feat? While some progress has been made in understanding mechanisms, relatively little is known about the evolution of regenerative ability. Which elements of regeneration are due to lineage specific evolutionary novelties or have deeply conserved roots within the Metazoa remains an open question...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1016/j.ydbio.2017.10.010

Authors


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Institution:
University of Oxford
Division:
MPLS Division
Department:
Zoology
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Zoology
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Funding agency for:
Aboobaker, AA
Publisher:
Elsevier Publisher's website
Journal:
Developmental Biology Journal website
Volume:
433
Issue:
2
Pages:
118-131
Publication date:
2017-11-30
Acceptance date:
2017-10-10
DOI:
EISSN:
1095-564X
ISSN:
0012-1606
Pubs id:
pubs:747133
URN:
uri:b1277201-8ca7-45ed-b8ad-e12e481c4f29
UUID:
uuid:b1277201-8ca7-45ed-b8ad-e12e481c4f29
Local pid:
pubs:747133

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